What move does the options market price into Spyre Therapeutics's report?

Implied ±25.8%, either direction · provisional.

How often does Spyre Therapeutics move more than the options market prices?

1 of the last 8 reports moved at least as far as the implied move.

SYRENasdaqPharmaceutical Preparations

Spyre Therapeutics, Inc. (SYRE) earnings date, market-implied expected move, and options open interest by expiry

99.08

pre 99.15 +0.11%

Pre-market06:24 ETdelayed

Open99.15Volume1.5MMkt cap$9.4B

Day99.15 – 99.1550%52-wk21.15 – 110.1888%

SYRE

Spyre Therapeutics, Inc.

OpenVolumeMkt capP/EEPSDiv yield

Day – 52-wk –

Expected move

Inputs

±25.8%implied · straddle

73.45124.63

spot 99.04exp Mar 19ATM strike 100ATM straddle 30.10IV 63%

Nov 4 closeprovisional

Expected move

Inputs

Next report

Feb 18

after close · in 105 days

est.Q4 FY26

Calendar

Next report

Last report

−0.23%

vs ±11.9% implied · ×0.02

shaded = implied · ▲▼ = realized

Nov 3 '26 · confirmed

Implied vs realized

Largest filed tie

—

Supply chain

13F top-10 QoQ

+15.24%

shares held · 10 largest managers

13F · Jun 30 '26128d lag

266 managers

Top fund weight

1.10%

SYRE weight · XBI

N-PORTJun 30 '26

4 funds

Last reportshaded = implied▲▼ = realized× = |realized| ÷ implied

Spyre Therapeutics (SYRE) is expected to report on Feb 18 after close (estimated date).

Implied vs realized

8 reports

1 of 8≥ implied

avg implied: ±18.4%
avg realized: ±5.1%

Feb 27 '25Feb 27 '25confirmed±20.8%▲+7.24%×0.35

May 8 '25May 8 '25confirmed±34.0%▲+9.64%×0.28

Aug 5 '25Aug 5 '25confirmed±24.9%▼−5.39%×0.22

Nov 4 '25Nov 4 '25confirmed±21.2%▼−0.57%×0.03

Feb 19 '26Feb 19 '26confirmed±12.0%▲+14.28%×1.19

Q1 FY26May 5 '26confirmed±8.3%▲+2.72%×0.33

Q2 FY26Aug 4 '26confirmed±13.8%▼−0.56%×0.04

Q3 FY26Nov 3 '26confirmed±11.9%▼−0.23%×0.02

quarterimplied−35%0+35%realized×

Q3 FY26±11.9%▼−0.23%×0.02

Q2 FY26±13.8%▼−0.56%×0.04

Q1 FY26±8.3%▲+2.72%×0.33

Feb '26±12.0%▲+14.28%×1.19

Nov '25±21.2%▼−0.57%×0.03

Aug '25±24.9%▼−5.39%×0.22

2 older reports

May '25±34.0%▲+9.64%×0.28

Feb '25±20.8%▲+7.24%×0.35

Shaded = implied · tick ▲▼ = realized · × = |realized| ÷ impliedSource: options EOD · implied at prior close · realized close to close

Implied vs realized

Positioning

OI · 4 expiries · Nov 3 close

0.67OI · 4 expiries · Nov 3 closeP/C open interest · Mar 19 · first expiry after the report

PUTS · chgexpiry · days · P/CCALLS · chgP/C

3560%Nov 2015d2.17164+2%2.17

63+2%Dec 1843d0.341850%0.34

1,0100%Jan 1571d4.832090%4.83

report · Feb 18 · after close · est.

620%Mar 19134d920%

ExpiryPutsCallsP/C

Nov 2015d3560%164+2%2.17

Dec 1843d63+2%1850%0.34

Jan 1571d1,0100%2090%4.83

report · Feb 18 · after close · est.

Mar 19134d620%920%0.67

Hatched = puts · solid = calls · bars scaled per expiry · chg = OI vs prior sessionSource: options EOD

Positioning

Linked exposure

scenario · straddle±25.8%

Funds 4

XBI±0.3%

IWM±0.1%

UWM±0.0%

VTI±0.0%

Dashed = straddleMethod Source: SEC filings · N-PORT · market data

Linked exposure

Revenue flow

No filed income statement.

Revenue flow

Intraday

No trades yet today.

Intraday

Event sensitivity

GDP ×1.17· ±4.0% vs ±3.4% · 19 releases

eventrelease day|move|up · n×base

GDPgross domestic product±4.0%12 of 19×1.17

PCEpersonal income & outlays±3.8%11 of 19×1.10

CPROFcorporate profits±3.7%6 of 12×1.08

PPIproducer prices±3.0%6 of 10×0.88

FOMCrate decision±2.6%14 of 24×0.76

CPIconsumer prices±2.4%5 of 10×0.70

NFPjobs report±2.3%6 of 10×0.68

Bar = avg |move| to ±5% · tick = ±3.4% avg day · ×base = |move| ÷ ±3.4% · min 6 releases

Earnings history

EPS 0.00 · consensus —

Quarter	Reported	EPS	Consensus
Q3 FY26	Nov 3 '26 · confirmed	0.00	—
Q2 FY26	Aug 4 '26 · confirmed	-29.56	—
Q1 FY26	May 5 '26 · confirmed	-0.74	—

Source: filed financials

Methodology

ties · implied moves · holdersMethod