Karyopharm Therapeutics Inc. · Brief

Next report

2 days

Nov 2 · before openest.Q3 FY26

Expected move

±54.6%implied · straddle

0.301.02

spot 0.66exp Nov 20ATM strike 0.5ATM straddle 0.42IV 398%

Oct 30 close

Expected move

—≥ implied

Q2 FY26±32.0%▼−1.97%×0.06

quarterimplied−35%0+35%realized×

Q2 FY26±32.0%▼−1.97%×0.06

Shaded = implied · tick ▲▼ = realized · × = |realized| ÷ impliedSource: options EOD · implied at prior close · realized close to close

Nov 2 report · est.

Bull2 of 3

+27.94%change in shares held by the ten largest reporting managers this latest quarter13F · Jun 30 '26

99managers reporting a position in the latest quarterly filings13F · Jun 30 '26

Bear2

7 of 22of the largest reporting managers cut their stake in the latest quarter13F · Jun 30 '26

25managers whose positions together make up four fifths of the reported value13F · Jun 30 '26

AI captions · Sep 28 '26once per report · top 2 per case

KPTI report session

No linked exposure.

Oct 21impliedImplied move: ±81.0% into Nov 2 earnings (Oct 21 close).Source

privateThesis 0 · Decisions 0 · Observations 0

No thesis.